WISE Srl (www.wiseneuro.com) is a medical device company based in Italy and Germany developing a genuinely new generation of implantable electrodes for Neuromonitoring and Neuromodulation.
WISE’s electrodes are foldable, stretchable, showing at wish unparalleled softness, enabling minimally invasive procedures and overcoming the major limitations of today’s electrode’s fabrication technologies. They allow to improve the treatment of patients that are already profiting from Neuromodulation, while at the same time expanding the use of Neuromodulation to fields and clinical indications in which the complex technical demands cannot be met by the current technology.
The electrodes are produced through a proprietary innovative technology, called Supersonic Cluster Beam Implantation (SCBI), which allows the metallization of stretchable and soft polymers without altering their mechanical properties. SCBI consists in embedding metal nanoparticles inside a preformed polymer base in order to form a conductive metal-polymer skin on its surface. Thanks to its SCBI technology WISE has built a technology platform enabling the design and realization of electrodes that can be applied to many different Neuromonitoring and Neuromodulation devices (WISEneuro leads).
WISE aspires to become a market leader for implantable leads in the medical device sector.
The company is currently concluding the CE certification phase for its first product for acute use: Cortical Electrodes for intraoperative monitoring. WISE is furthermore developing the first percutaneously-implantable paddle lead for Spinal Cord Stimulation (SCS). WISE’s paddles will be foldable, therefore combining the strengths of paddle leads - directional stimulation and precise selection of the stimulation point - with the versatility, simple positioning and easy removal of percutaneous leads. WISE’s Foldable SCS Paddle Leads have the mission to overcome today’s trade-off between leads’ performance and invasiveness of the surgery.
WISE was founded in 2011 by four scientific partners who are the inventors of the SCBI technology, is managed by an international Board of Directors and is led by one of the founders (the CEO Luca Ravagnan). As of today, the Company has collected more than €10 million from a pool of international VC Investors, among which High-Tech Gründerfonds (DE), b-to-v Partners (CH), Atlante Venture (IT) and Principia Sgr (IT). Since 2016 the Company has established its Production Plant of 1000 m2 in Cologno Monzese (Milan, Italy), comprising cleanrooms and production laboratories compliant for the manufacturing of implantable medical devices.
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